Melrose Homes For Sale & Real Estate - 45 homes

Remarks: Welcome to this touch of paradise hidden from the road. Approximately 600 ft from the road, this spacious 3 bedroom/ 2 bath brick home is situated on two parcels totaling 4.47 acres. Wood burning fireplace with built in benches on each side. Garage has been converted into a master bedroom with 2 built in closets, a bathroom, and a laundry room. Large kitchen with farmhouse sink, lots of counter space, soft close cabinets, and a pantry. All appliances stay. Lots of storage throughout the home. Built in Ikea shelves in family room. Enjoy your coffee while sitting out on the back deck overlooking the back yard. Chicken coop in backyard. Well bladder tank replaced within the last 10 yrs. Metal roof 1995 and HVAC installed 2002. Ceiling and interior walls recently painted. Shipping container used for storage. Green shed has electric. 300' frontage of Lake Serena. Two entrances on property. Country living at it's best! Additional Parcel ID: 10-09-23-0000-0282-0000/732 SR26 - 1.84 acres

Listing is courtesy of: HELEN HERSEY REALTY (352-473-8882)

Listing Agent: Helen Hersey (352-473-8882)

Remarks: This charming 2/2 located just outside of Melrose on Lake Mandarin offers quiet country living with a modern touch. Just 14 minutes to beautiful lake Santa Fe. Situated on over two and a half acres this cottage home feels warm and inviting on the inside. Solid maple cabinetry topped with granite counter space in the kitchen and bathrooms offer a modern touch to the rustic setting. The house has tile floors throughout the main living areas and carpet in the spacious bedrooms. Sit on the screened porch while enjoying your morning coffee and watch the turkey and deer roam about. Cool off in the pool on a warm summer afternoon. In the evening watch the water fowl and osprey fly around the lake. Call today to book your showing. This one wont last long!

Listing is courtesy of: KELLER WILLIAMS GAINESVILLE REALTY PARTNERS (352-240-0600)

Listing Agent: Chase Rossi (352-215-7251)

Remarks: Charming country cottage in the heart of downtown Melrose. This artist inspired, custom-built home features an open floor plan with high ceilings, ceramic tile flooring and lots of natural light! The kitchen has a gas range, SS Refrigerator, and farm sink. The primary bedroom has a half bath. Washer & dryer and included. The kitchen opens onto a 16x16 ft wood deck with hot tub and pergola and fenced back yard. There is a tool shed and a covered RV carport with concrete pad. Fully Finished 10x16 storage shed with 2 loft spaces and electric was used as artist studio. The corner lot has fruit trees, palms and a wildflower/pollinator garden. High speed cable internet access via Kenetic by Windstream. LOW Clay Electric Cooperative rates and LOW Putnam County taxes. Plenty of room to add an addition, ADU, or detached dream home while you live onsite. Rural ambiance, but located only blocks from Heritage Park. Walk to Mossman Hall, Melrose Bay Art Gallery, Melrose Community Center, and renowned Blue Water bay restaurant. Only 20 miles to Gainesville or Palatka. Melrose offers wonderful Small-town vibes and is well-known for its rich history, and its vibrant music, arts & culture scene. Become a part of this amazing community!

Listing is courtesy of: PAIS REALTY (352-215-1580)

Listing Agent: David Pais (352-215-1580)

Remarks: Welcome to this beautifully built 2024 home located on a quiet, wooded lot in Melrose. This 898 sq ft, 1-bedroom, 1-bath home with a bonus room offers modern, low-maintenance living in turn-key, like-new condition. The open-concept layout features luxury vinyl plank flooring, neutral finishes, and abundant natural light. The kitchen includes granite countertops, stainless steel appliances, white cabinetry, and a functional island, opening seamlessly to the living area. The primary bedroom is well-sized with ample closet space, while the bonus room provides flexibility for a home office, guest room, or nursery. The bathroom is finished with modern fixtures and a tiled tub/shower combo. Sliding glass doors lead to a peaceful backyard surrounded by mature trees. With new construction quality and no updates needed, this home is ideal for a first-time buyer, downsizer, or anyone seeking a move-in-ready property in a quiet North Florida setting.

Listing is courtesy of: TREVOR WATERS REALTY INC (352-473-7777)

Listing Agent: Branden Waters (352-222-2888)

Remarks: Fully renovated 2 bedroom, 2 bathroom waterfront lake home on 1.5 acres, offered fully furnished and designed for comfort, style, and long-term peace of mind. This rare Melrose lakefront property has been extensively remodeled, with all major and costly systems already replaced—making it truly move-in ready. Professionally renovated by Iron House Florida, LLC, a local Central Florida investor. Upgrades include a new plumbing system, new well pump, pressure tank, and new pool pump, with a new roof to be installed prior to closing. The interior has been thoughtfully updated and features a fully remodeled kitchen with quartz countertops, stainless steel appliances, and modern finishes throughout. Spa-style bathrooms, fresh interior and exterior paint, abundant natural light, and a large inside laundry room complete the polished living space. Outside, enjoy the screened inground pool and expansive lakeside lot with plenty of room for an RV, boat, work vehicles, gardening, or a future workshop. Three storage sheds provide added storage and flexibility. Located on a quiet street with no HOA, and conveniently commutable to Orange Park, Gainesville, and Palatka. A rare opportunity to own a fully upgraded, furnished lakefront retreat.

Listing is courtesy of: CENTURY 21 LAKESIDE REALTY (352-475-1269)

Listing Agent: Trey Fields, Iii (352-222-9251)

Remarks: Lakefront living with built-in income potential! This well-maintained home sits on a landscaped 1.19-acre high and dry lot in a quiet neighborhood just minutes from downtown historic Melrose. 3 bedrooms, 3 full bathrooms (main residence is 2 bed / 2 bath), an open flow, tons of storage, and a fully screened patio w/ hot tub. Additionally, there is a 900-sqft semi-finished basement with drywall, electrical, and plumbing. Use it for massive storage, finished into a private office space, etc. Separate storage area for lawn mowers and yard tools plus a 1-car garage and ample additional driveway parking. A full efficiency apartment with kitchen and full bathroom is currently rented for almost $1,000/MO on a short-term lease. Perfect for passive income, the perfect in-law suite, or a guesthouse. All of this in a prime location less than 30 minutes to Gainesville and just 5 minutes up the road to the almost 6,000-acre Lake Sante Fe public boat launch! Welcome Home!

Listing is courtesy of: EPIQUE REALTY, INC. (888-893-3537)

Listing Agent: Walter Key (757-635-3645)

Remarks: Located near the historic town of Melrose, this spacious 3-bedroom, 3-bath home sits on over 1.23 acres of lush and peaceful landscape. Deeded Access to Melrose Bay includes a 25ft easement with dock for access to Lake Santa Fe to enjoy beautiful views, fishing and kayaking. You are walking distance to small town charm to enjoy art galleries, restaurants, and parks. Open floor plan with lots of natural lighting. Kitchen is spacious and is open to a sunroom with nice built-ins. Nice Terrazzo flooring in main arears of the home are hidden under carpet! With generous living spaces and an ideal location, this home is a rare opportunity to enjoy both comfort and the vibrant lifestyle of downtown Melrose.

Listing is courtesy of: CB ISAAC REALTY (352-475-2199)

Listing Agent: Ronald Blake (352-235-1644)

Remarks: Step back in time while enjoying modern possibilities with this beautifully preserved historic home, originally built in 1885 by Henry Baldwin of Naugatuck, Connecticut. Nestled in the heart of picturesque Melrose, Florida, this two-story residence offers a rare blend of heritage, charm, and versatility.Featuring 4 bedrooms and 2.5 bathrooms, the home boasts classic architectural details and inviting living spaces filled with warmth and character. Relax and unwind on the front or back porches, perfect for enjoying Florida’s tranquil surroundings, morning coffee, or evening gatherings.The property also includes a quaint metal-roofed workshop, brimming with potential—easily convertible into a charming guest cottage, studio, or creative retreat. There is also another small out building perfect for storage.Adding to its appeal, the property is zoned for home-based business use, offering a unique opportunity. Operate your business right from home, with the convenience of on-site work permitted as long as the owner resides on the property. Melrose is a small town with lots of charm. Boasting only one traffic light but twice as many art galleries and several lakes available for swimming, boating and other water activities. Melrose is also located 20 minutes from the city of Gainesville, home of the University of Florida and all that comes with a college town. Whether you're seeking a distinctive residence, a live/work opportunity, or a piece of Florida history, this property offers endless possibilities. Seller is open to owner financing.

Listing is courtesy of: CENTURY 21 LAKESIDE REALTY (352-475-1269)

Listing Agent: Teri Sapp (352-494-3724)

Remarks: COLORFUL CEDAR SIDING HOME ON THE STRIP IN DOWNTOWN MELROSE HISTORIC DISTRICT !! HOME IS JUST BLOCKS AWAY FROM LAKE SANTA FE RAMPS AND FAMILY FRIENDLY PARKS AT MELROSE BAY. PROPERTY GENTLY SLOPES, IS HIGH AND DRY AND PARTIALLY FENCED. INTERIOR HAS 2 MASTER BEDROOMS AND 2 MASTER BATHS, ENTERTAINMENT ROOM, OVERSIZED GARAGE, OFFICE WHICH COULD BE A 3RD BEDROOM. DINING ROOM WITH EAT IN KITCHEN HAS BREAKFAST BAR AND LARGE PANTRY. PROPERTY GENTLY SLOPED AND HAS AMAZING SOIL FOR YEAR ROUND GARDENS , THE YARD IS ADORNED WITH AZALEAS, ELEPHANT EARS, PECAN, CITRUS AND BANANA TREES. ATTACHED GARAGE W/ 2 LARGE EXTRA BUILDINGS ONE IS A MINI APARTMENT GREAT FOR AN AIRBNB. ROOF HAS A UNIQUE TUBE SKYLIGHT FOR REAL NATURAL LIGHTING IN THE DINING AREA, ROOF IS ONLY 5 YEARS OLD. 15 MINUTES TO GAINESVILLE AND WALKING DISTANCE TO THE NEW WILDFLOWERS MUSIC PARK, DOWNTOWN LIVE MUSIC, FOOD TRUCKS, RESTAURANTS, SWIMMING, BIKING, FARMERS MARKETS, ART GALLERIES. COME VISIT HISTORIC MELROSE AND SEE WHY THIS SMALL TOWN IS SO ATTRACTIVE.

Listing is courtesy of: FLORIDA HOMES REALTY & MORTGAGE (904-996-9144)

Listing Agent: Carl Buz (352-327-0535)

Remarks: SANTA FE CANAL WATERFRONT HOME Seems the Lake Region of North Central Florida is being discovered by so many now wanting out of the CITY TRAFFIC AND CHAOS and getting back to enjoying a rural lifestyle and lake living. Here in Historic Melrose Florida is this 2/2 all metal Morton Home located in a private community on a paved road. The home is uniquely designed with quality construction. The split floor plan allows private door access to either side, plus roadside. Just a few steps and you are at your screened-in dock with an open deck and sheltered boat lift. The property also includes a 20x20 2 car carport and a large 12x16 storage shed. The famous Santa Fe is a 6,000 acre fully recreational lake allowing you all types of activities: wake surfing, kayaking, tubing, fishing, jet skiing, swimming, sailing, and more. From your dock to the big lake, you're only minutes away. This location is also conveniently located for commuting to Gainesville, Palatka, Ocala, Starke, and Middleburg Florida - but the true highlight is being part of Historic Melrose. Yes, it’s only a one-light town, but it is alive with activity. Besides its natural beauty and friendly atmosphere this amazing little big town offers some fine restaurants, general shopping stores, fresh produce stands, doctors, a senior center, cultural activities, even at Mossman Hall there are art shows, dances, and various classes. Live music seems to be somewhere every week entertaining the folks in and around our amazing lake region. You're welcome to drive by this home anytime but be sure to visit the Historic District of Melrose - you'll notice the towns charm immediately and why many are wanting this special way of life out here in the Lake Region of North Central Florida. NOTE: This home may come completely furnished

Listing is courtesy of: CENTURY 21 LAKESIDE REALTY (352-475-1269)

Listing Agent: Roger Buz (352-514-7000)

Remarks: Enjoy peaceful country living with this 3 bedroom, 2 bathroom mobile home. Sitting on over an acre lot, the mature trees and open surroundings provide a sense of privacy while maintaining easy access to nearby amenities. Located just minutes from Melrose and Lake Santa Fe, this property offers the best of rural living with convenient access to Gainesville (approximately 40 minutes) and Jacksonville and St. Augustine (just over an hour).

Listing is courtesy of: KINGS HOME REALTY LLC (941-504-0016)

Listing Agent: Garrett King (941-504-0016)

Remarks: Uniquely perched on a 15 ft bluff above Lake Santa Fe, this expansive custom lakefront estate offers a grand scale and timeless elegance, perfect for those seeking a luxurious retreat. The heart of the home is its open kitchen, designed for effortless entertaining, flowing seamlessly into a spacious living area with room for a grand piano and dining space, all framed by 2 story ceilings that amplify the sense of grandeur. Almost every room captures stunning lake views, immersing you in the serene beauty of the surroundings. A dramatic custom steel circular staircase with oak treads milled from the property is designed to preserve the breathtaking vistas and add an artistic touch. The primary suite, nestled on the third floor nearly 40 ft above the lake, is a true sanctuary of luxury and tranquility. It opens to a private porch where you can savor morning coffee or evening wine while gazing out over the shimmering lake—a perfect spot for quiet reflection. Adjacent to the suite, a cozy keeper room offers a private retreat for reading or relaxation, bathed in natural light and lake views. The primary bathroom elevates the experience with a spacious, curbless walk-in shower designed for seamless accessibility, a corner soaking tub ideal for unwinding after a day on the water, and a custom double vanity that adds a touch of elegance to your daily routine. For the young or young-at-heart, a secret children’s room offers a magical hideaway, accessible only through a wardrobe, evoking a sense of wonder. Inside, 4 children’s bunk beds create a cozy retreat for sleepovers or imaginative play, making this space a delightful surprise for families. This home is built for versatility and comfort, with porches on all four floors, each offering a unique perspective of the lake’s shimmering waters—perfect for morning coffees or evening gatherings. The elevator accesses all four floors including the full-size attic, featuring 8 ft ceilings, making the home fully accessible for all. The attic is plumbed for an additional bathroom and offers ample space to create more bedrooms, making it ideal for growing families or guests. The first floor is a self-sufficient 2-bedroom apartment, complete with its own kitchen and living areas, operating independently from the main house for ultimate flexibility. Step outside to the lakefront, where a gentle beach entry offers an easy walk-in swimming area, perfect for family fun or a refreshing dip. The ipe wood dock extends into the lake, featuring a boat lift for your watercraft and boasting over 10 ft of water depth at its end—ideal for boating enthusiasts. The sunsets here are magical, painting the sky in vibrant hues as you unwind. This home is truly unlike any other and must be seen in person to experience all it has to offer.

Listing is courtesy of: SHEEPCO REAL ESTATE GROUP (904-701-0860)

Listing Agent: Ryan Hiebsch (904-710-0376)

Remarks: Lake life starts here with deeded access to the highly sought-after Swan Lake, only a quick golf cart ride from your doorstep. This well-maintained 3-bedroom, 2-bathroom features a comfortable and inviting layout designed for everyday living. Situated on a desirable corner lot, outside you will enjoy a spacious yard, a storage shed for all of your lake gear, and a back patio to enjoy your morning coffee while listening to nature. Whether you're relaxing at home or hosting guests, this property provides the perfect balance of functionality and warmth. Spend your days enjoying boating, fishing, or soaking in peaceful lake views, all without the premium price of direct waterfront. Located in the heart of Melrose, you'll love the small-town feel while still having the luxury of both Comcast & Xfinity internet. If you've been searching for affordable lake-area living with access to one of the region's most desirable lakes--this is it!

Listing is courtesy of: CB ISAAC REALTY (352-475-2199)

Listing Agent: Calee Hinson (386-406-0119)

Remarks: Tucked away at the very end of Island Road, this charming rustic retreat offers a rare opportunity to enjoy true waterfront living on the Santa Fe Canal—just steps from where it opens into Lake Santa Fe. This 3-bedroom, 2-bath home blends cozy character with thoughtful updates, including a beautifully refreshed kitchen and bathrooms, along with a durable new metal roof for peace of mind. Inside, you’ll find warm, inviting spaces that make you feel right at home from the moment you walk in. Out back is where this property truly shines. A massive Florida room creates the ultimate entertaining space—complete with a built-in bar area and pool table—perfect for hosting friends, game nights, or simply relaxing after a day on the water. Even better, all furnishings can stay, making this a turnkey opportunity. Step outside and take in peaceful canal views from your backyard, with direct access to Lake Santa Fe just moments away. As the last home before the canal opens to the lake, you’ll enjoy a unique blend of privacy and prime positioning for boating, fishing, and waterfront living. Additional features include a large workshop with electric—ideal for hobbies, storage, or projects—and a newer dock ready for your boat and lake days. Whether you’re looking for a full-time residence, weekend getaway, or income-producing vacation rental, this one-of-a-kind property delivers the best of North Florida lake life.

Listing is courtesy of: CB ISAAC REALTY (352-475-2199)

Listing Agent: Calee Hinson (386-406-0119)

Remarks: Discover the perfect blend of investment potential and natural beauty at 107 Eliam Road. This 3 Bedroom 2 Bath home sits on nearly an acre of private, fenced land with no HOA restrictions. Built for durability with a metal roof and HardiPlank siding, the residence features a screened porch and deck designed for enjoying the peaceful surroundings. Whether you're looking for a high-demand rental or a quiet retreat near the region's famous lakes, this centrally located property between Gainesville and Palatka is a rare find. Investment & Durability Solid Construction: Built with HardiPlank-type siding and a metal roof, this home is designed for longevity and low-maintenance costs.No HOA: Enjoy total freedom with no annual association fees and no restrictive covenants, making it ideal for storing boats or RVs. Turnkey Ready: The home is currently vacant and features central air, central heating, and durable vinyl flooring. Flexible Use: Zoned as Agricultural (AG), the land provides more versatility than standard residential lots. Natural Surroundings & Outdoor Living Expansive Lot: The property is fully fenced with wire fencing, providing a secure space for pets or gardening. Outdoor Oasis: Multiple outdoor spaces include a front porch, deck, and a screened-in rear porch, allowing you to fully enjoy the quiet Melrose atmosphere. Heart of the Lakes: Located in the celebrated Melrose lake region, you are minutes away from some of the best fishing and boating in North Central Florida. Location & Accessibility Centrally Positioned: Situated conveniently between Gainesville and Palatka, providing easy access to city amenities while maintaining a rural lifestyle.Local Convenience: The property is located near Historic Melrose, with lots of music restaurants , art walks, farmers markets ,Schools the new 270 acre Wild Flowers Music Park, as well as Santa Fe Lake, a 6000 fully recreational spring fed lake. Come see why this quaint town is so attractive !!

Listing is courtesy of: FLORIDA HOMES REALTY & MORTGAGE (904-996-9144)

Listing Agent: Carl Buz (352-327-0535)

Remarks: Paradise on the lake. 3 bedroom 2 bath home with fireplace. Kitchen looks out to lake along with formal dining area and laundry area. Concrete picnic table under the trees to enjoy the view. Large workshop 24 x 27 with storage and attic. Living room windows have glass shelves. Large workshop with lots of storage. Drought has lake low and roads are soft.

Listing is courtesy of: CRIDLAND REAL ESTATE (352-344-5535)

Listing Agent: Lee Harris (352-817-1987)

Remarks: Well-maintained triple-wide mobile home located in Ashley Lake Plantation on 1.02 acres with AG zoning, offering 2,150 square feet of heated and cooled living space. This spacious 4-bedroom, 3-bath home features an open island kitchen with stainless steel appliances, a pantry, and an inside laundry room. A versatile bonus room adjacent to the primary suite is perfect for a home office or flex space. Relax in the family room with a cozy fireplace and enjoy peaceful water views. Roof replaced in 2019. Oversized shed/workshop with ramp access, perfect for storage, hobbies, or workspace needs. Open interior offers flexible use for equipment, tools, or recreational gear. Great functional space with easy access. Conveniently located near historic downtown Melrose and Lake Santa Fe, with an easy commute to Gainesville and Palatka. Schedule your tour today!

Listing is courtesy of: CENTURY 21 LAKESIDE REALTY (352-475-1269)

Listing Agent: Trey Fields, Iii (352-222-9251)

Remarks: Welcome to this spacious 3-bedroom, 2-bath lakeview home on Mandarin Lake in the heart of Melrose. Tucked among mature trees in a peaceful rural setting, this property offers the perfect blend of privacy and comfort. Inside, you'll find bright, airy living spaces including formal living and dining rooms, a cozy fireplace, and a sunroom filled with natural light and stunning water views. The primary suite features a private bath, while a bonus room with plumbing and A/C provides flexibility for an office, hobby space, or workshop. Enjoy a 2-car garage and ample outdoor space for all your hobbies and entertaining. If you're looking for tranquil lake living without sacrificing convenience, this is it.

Listing is courtesy of: TREVOR WATERS REALTY INC (352-473-7777)

Listing Agent: Branden Waters (352-222-2888)

Remarks: Welcome to peaceful country living in Melrose on approximately 5 beautiful acres, featuring a 2021 manufactured home surrounded by mature trees and open skies.The home features 3 bedrooms, 2 bathrooms, and 1,344 square feet with a bright open layout designed for comfortable everyday living. A spacious screened porch extends the living area outdoors and creates the perfect place to enjoy morning coffee, watch wildlife, and relax in the quiet rural setting. The property itself is full of possibilities. Highlights include a scenic pond, solar panel system, carport, and pole shed, offering flexibility for hobbies, storage, or small homestead use. RV hookups are already in place, making it ideal for travelers or visiting guests. The solar system is transferable, with any remaining balance to be assumed by the buyer. Additional battery storage is available for an added monthly fee. Established fruit trees, including mulberry, orange, and tangerine, add to the property's charm while providing seasonal harvests. With well and septic already in place and plenty of room for gardens, animals, or outdoor activities, this property offers the space and freedom many buyers are searching for. Whether you're looking for a peaceful retreat, a homestead opportunity, or simply room to breathe, this Melrose property offers endless possibilities.

Listing is courtesy of: PEPINE REALTY (352-226-8474)

Listing Agent: Betsy Pepine (352-226-8474)

Remarks: Discover a truly unique architectural home on 6.75 acres with serene pond frontage in Melrose. This custom dome-style residence features soaring ceilings, open-concept living, and a dramatic spiral staircase to a loft-style primary suite overlooking the main living area. Distinctive design creates an airy, light-filled interior with rare character. Additional bedrooms on the main level offer flexible living space. Detached garage/workshop for storage or hobbies. Updates include newer HVAC, new hot water heater, and whole-house generator. Enjoy privacy, natural surroundings, and room for recreation or gardening. Convenient to Melrose, Keystone Heights, and commuting distance to Gainesville. Ideal for buyers seeking a distinctive retreat, artist’s haven, or private homestead with nature views and unmatched architectural character. A rare opportunity to own a truly iconic dome home in North Florida. Schedule a private tour today. Don’t miss this architectural gem!

Listing is courtesy of: CENTURY 21 LAKESIDE REALTY (352-475-1269)

Listing Agent: Trey Fields, Iii (352-222-9251)