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7521 NE 222ND ST,  MELROSE, FL 32666

MLS# GC541231.  2 beds.  2.0 baths.  Single Family Home.  Active

$4,840 in taxes (2025)

$595,000

 

Remarks:

Some homes check the boxes. Others make you feel something the moment you arrive. Originally built in 1956 as two neighboring fish camps, this one-of-a-kind waterfront home has been thoughtfully transformed into a warm, inviting retreat while preserving the character that makes it so special. Sitting on 0.7 acres with more than 100 feet of shoreline on Big Lake Santa Fe, this is the kind of property where mornings begin with breathtaking sunrises over the water and evenings end on the porch after a day on the lake. With nearly 500 acres of surface water and depths reaching up to 26 feet, Big Lake Santa Fe is one of North Central Florida's most treasured lakes, offering year-round boating, skiing, fishing, paddleboarding, and endless days on the water. The property even includes its own natural lagoon with a small boat ramp, and the dock was extensively improved in 2023 with new pilings where needed, an extended platform, and a 5, 000-pound Dolphin boat lift ready for your ski boat or pontoon. Inside, every room reflects the care and creativity of the current owners. The remodeled kitchen features custom cabinetry, updated countertops, appliances, and fixtures, while beautiful luxury vinyl plank flooring flows throughout the living spaces and new tile enhances both bathrooms. Thoughtful details—from the wood accents and designer lighting to the carefully chosen finishes—create a home that feels both timeless and effortlessly welcoming. One of the highlights is the incredible 31-foot screened porch, added in 2020. It's the perfect place to sip your morning coffee as the sun rises over the lake, watch afternoon storms roll across the water, or gather with friends long after the sun goes down. The home offers 2 bedrooms, 2 baths, plus a versatile bonus room that could easily serve as a third bedroom, office, bunk room, or creative studio. A unique guest bath connects directly to the utility room and exterior door, making cleanup after swimming, fishing, or working outdoors incredibly convenient. Outside, the property continues to impress. Mature cypress trees frame the lake without stealing the view, while a fully fenced yard with an electric gate offers privacy and peace of mind. A powered workshop and separate storage shed provide plenty of space for tools, hobbies, lake toys, and equipment. Nearly every major component has been improved, including a metal roof, updated windows and doors, remodeled kitchen and bathrooms, luxury flooring, exterior paint, new water heater (2026), gutters with guards, finished laundry room, sump pump (2021), septic service, and much more—allowing the next owner to simply move in and start enjoying lake life. Whether you're searching for a full-time residence, a weekend escape, or a vacation rental with exceptional appeal, this property offers something that's becoming increasingly difficult to find: authentic character, modern updates, and a front-row seat to one of North Central Florida's most beautiful lakes. Some houses are just places to live. This one is where memories are made. Need more room for family or guests? The beautifully built 2021 custom home directly across the street is also available. Purchase both together at a discounted package price to create your own private Big Lake Santa Fe retreat. (GC541232)

Quick Info:

  • Listing is courtesy Of: KELLER WILLIAMS GAINESVILLE REALTY PARTNERS ((352-240-0600))
  • Listing Agent: Lindsey Johnson ((352-663-4347))
  • Days on yellowkey: 20
  • Property Type: Single Family Home
  • Beds: 2
  • Baths: 2.0
  • Living Area Square Feet: 1042
  • Built 1956
  • Taxes: $4,840 (2025)
  • Garage Spaces: ()
  • Square Feet: 1338
  • Fees: $0
  • Alachua County
  • Terms: Cash, Conventional, FHA, USDA Loan, VA Loan
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  • Occupancy Information: Vacant
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History:

DateListing TypeDays on yellowkeyMLS#EventPrice% Chg$/sqftSource
6/27/2026Sale20GC541231listed for sale$595,000-444.6935MLS




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